The Bruins (25-6, 17-5) won 30-26, 30-21, 33-35, 30-22 in one hour and 55 minutes before 612 fans at Crawford Hall.
The Anteaters ended their season at 12-17 overall and 6-16 in league play. UCLA's victory assures that it will finish no worse than third place in the MPSF standings.
In team statistics, the Bruins out-blocked the Anteaters, 12.5-8.0 and limited them to a hitting percentage of .231. UCLA served 10 aces to UCI's six.
Erick Helinihi and Jimmy Pelzel led UCI with 16 kills each.
UCLA will host a quarterfinal MPSF playoff match on Apr. 20 at 7 p.m. in Pauley Pavilion. Complete playoff pairings will be released on Sunday, Apr. 14.